I think there is a lot of variability from one person to the next. By one week into my Orgovyx treatment (I'm about four months in now), my libido was gone, spontaneous erections were gone, and hot flashes had begun.

Issues with libido and erections persist. The hot flashes seem to come and go - I'll go for a week or two with no significant issues, and then (for example, about a week ago) I'll have a day or two with multiple hot flashes of the "sweat dripping down the back of my neck" variety.

I've gained between 15 and 20 pounds while on Orgovyx. Have tried to maintain an exercise routine, but it's winter here, and the Orgovyx and six weeks of EBRT have left me lazy as hell. Headed to warmer climes later this week and I hope to get back into daily exercise.

Only about seven weeks to go - looking forward to the Ides of March!