I had one sided face swelling for years but only lasted 2-3 days about every month or so. Went to every dr possible and no one knew what caused it . Finally went to National Jewish Health in Denver, CO and saw an immunologist. After several visits, tests, etc she recommended an Xolair injection which is for asthma & hives (neither of which I have) Well the injections work!!! I’ve been getting 2 injections every 4-5 weeks for over 7 years! They cost $6000! Each visit. My insurance covers or I wouldn’t be getting them. My face no longer swells. If I go for shots at 6 weeks there is slight swelling but nothing like I had (looked like I had a golf ball in my cheek)