I was really having a hard time with the side effects and after 18 months using Lupron my PSA was undetectable so I discontinued it. Now after 18 months w/o my PSA is .01, which was expected. Urologist has set a threshold of 2 before we reconsider treatment.
My Gleason score was 8, stage 1, and I would have preferred surgery but I was having some severe blood pressure problems and the surgeon flat out told me I'd die on the table. That left me with the only option of hormone treatment and 20 sessions of radiation. Hope this helps.