Hi Mycole and Beebe-
My GI put me on cholestyramine and I did take it for about 8 mo. until I discovered two things. First of all, even though I took precautions I started to develop cavities. (I actually rolled the powder form into tablet form to bypass having to drink the sugary substance.) Second of all, after deep-diving into research produced an article that said that it can cause liver damage, although I'd have to go through all of my research papers to show exactly where I found it; something which I could do if need be. So, I decided to substitute with acacia 'Senegal' powder. So far so good. It has been regulating the bile salt for me pretty well. Next step for me to take care of is to get tested for any and all deficiencies that the bile acid malabsorption has caused. It seems to be rearing its ugly head and is actually something that I'm blaming on my GI doc because they haven't been listening to me. I have known for some time that I have been suffering from fat and sugar malabsorption but since my stool tests appeared to be normal they refused to acknowledge it. Well, we know our own bodies and since weight loss is telling me (common sense) that I am not absorbing nutrients that they're tests were inaccurate. They were supposed to tell me to eat a high-fat diet prior to taking the test and they did not. Hope this helps somone.