Slight increase in CA125
For the first time in 8 months my CA125 has increased from 4 to 5. I know that the number is low, but since it is my first increase since chemo, it is hard not to worry. I had seven rounds of chemo, complete hysterectomy, and am now on Avastin until June 2025. What should I watch besides the CA125 number? Thank you.
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How often do you get tested for CA125 level? The very little increase you report is nothing to worry about. Do you get CT scans? Do you get your blood and urine checked before every infusion? Do you have other symptoms to report to your doctor?
I wouldn't worry about slight increases. These test look at your current levels and they do fluctuate
@mharrill11951 Does your oncologist order the CA125 tests? If yes, then have you talked with your oncologist about what this very slight increase might mean?
I have had a one point increase and they said it was nothing to be concerned. My ca125 usually ranges in the 12-14 range. I get tested every three weeks with my zirabev infusion. I’m 11 months out from end of frontline chemo. I have to tell you I was freaked about a one or two point increase as well but it did come back down on the next one. I read some article about not to worry unless over a five point increase but truly I think you can find just about anything you want to hear on the internet. Hope this helps.
I have ca 19-9 and ca 15-3 checked as well. Actually, ca 125 was only checked a couple of times initially. The second time, after chemo, ca 125 returned to a normal range and so was never rechecked. I don't know why. But ca 19-9 skyrocketed a few months after chemo and keeps on climbing. Ca 15-3 remains out of bounds too. No one has explained why this is happening, so I've done the research and see that 19-9 especially is also a marker for endometrial cancer. It is usually associated with pancreatic cancer, which I do not, as far as I know, have.
Hope this helps