I took losartan for 20 years. But I took the brand version. I had a great insurance company. Suddenly they did not pay and I was switched to the generic version. About the third day I wound up on tbe floor passed out. I read many many medical articles and came to the conclusion that tbe generic I took somehow released too much drug into my system too quickly.
I paid for the brand version - a month’s worth (it was very pricey then but is not horrible now) and had no problem at all.
I did switch to a different drug, which took me a long time to figure out to take to keep side effects at bay but get optimal blood pressure control.
Both a friend and my husband had the same problem. I don’t know if it is quality control—
Or what. We pay for the brand version for my husband.
I had an interesting similar issue with zocor - simivastin.
My insurance company pays for that brand version because we were able to demonstrate through pharmacogenomics and careful data recording of lab values (ALT and AST were 5 times upper limit of normal) that my liver cannot handle the generic version.