I only took Effexor for a month....50mg tabs, titrated up to 2 tabs daily (immediate release, not xr). One day I forgot a dose (only at 75mg daily at this point) and felt horrible (nausea, dizziness, brain zaps, etc.) It wasn’t until I got home from work that I remembered my missed dosed. It was almost time for my next dose so I took it immediately. Within 45 minutes I felt 100% better....all of my symptoms had subsided and I felt normal. Thought that was weird,but continued with the titration up to 100mg daily within the next couple days. After only 2 days at that dose I decided I didn’t want to take this medication anymore because of the more noticeable side effects, so started to titrate back down. Visited my doctor a short while later and she agreed, I was down to 1 tab daily (1/2 morning and 1/2 night). She suggested going down to 1/2 daily, then every other day, then stop. She recognized that it can be difficult to come off of and told me to supplement the “off” days as needed until I’m off completely. Got down to 1/2 tab daily for a week, then decided to try every other day. Didn’t go as planned....ended up taking a 1/4 tab just to get some relief. Totally worked.....just a 1/4 of a tab (12.5mg) made me go from feeling like death to completely normal in less than an hour. I tried taking that dose for a week before trying the every other day again. Yesterday was my first successful skip day. The only reason it worked is because I didn’t start feeling the withdrawal symptoms until nighttime....approx. 3 hours before bedtime, so I just laid on the couch until it was time to go to sleep...it seems like as long as I don’t move I don’t notice the symptoms so much. In the morning however, I had to take my 1/4 tab as soon as I got up. Today when I got home, I started getting the withdrawal symptoms again, but instead of taking another 1/4 tab I decided to try my favorite pain reliever (PainAid, available from Amazon.....only thing that seems to work for me if anyone else finds that the normal Aleve/Advil/Tylenol/whatever doesn’t work...) and although it didn’t remove the symptoms completely....I was able to at least function normally (make dinner, do laundry, have a normal conversation with my husband, etc...haha) so Yay!! I’m hoping I can have another skip day tomorrow by just taking the pain reliever when I start feeling the symptoms...we shall see! Anyways, just wanted to share in case this remedy helps anyone else trying to get off this horrible medication....btw I was on 2 other meds like this with only slight side effects (mainly tired all, the time)...nothing like what I’ve experienced with Effexor.