← Return to Signatera CT DNA Test: What numbers have you seen on your tests?

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@mnewland99

Are you basically saying that the Signatera is more accurate at diagnosing microscopic residual disease (is the same thing as microscopic cells lingering about which can lead to metastasis?) than the Guardant360 which goes by blood work rather than tissue? I just got Guardant results online (dr out of town) and it didn’t detect any mutations, including KRAS. These type of tests are all new to me so I dint know anything about them yet. Seems like Guardant360 is good for deciding which clinical studies might be appropriate; but I dint know for sure if this is the purpose of the test. Originally, I thought it was to detect those sneaky microscopic cells.

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Replies to "Are you basically saying that the Signatera is more accurate at diagnosing microscopic residual disease (is..."

Actually, correction on my above response. There were a lot of mutations detected from my Guardant360 testing, but apparently they were predicted to be benign or unknown significance. TP53 was present, but of unknown clinical significance. No KRAS in this sample, though was detected in tissue of pancreas following my surgery back in 2022.