Radiation for 70 yr old (glioblastomas grade 4)?

Posted by antoines @antoines, Jan 20, 2024

Good afternoon,
A friend of mine learned that her dad was diagnosed with glioblastomas (grade 4.) He is 70 years old. He did the surgery and the surgeon asked the family whether to proceed with the chemo and radiation.
At this moment, he can barely walk.
The radiation will be around 8 weeks and we were wondering what would be the benefit of it. Reading articles, it seems that for his age, the gain would be marginal and if it is to gain 3 months more but 2 of them (at the start) are lost in daily radiation at the hospital, is it worth it?
Also, we were wondering as one of the potential benefit would be an health improvement (after some potential difficult moment during the chemo) but we could not find whether or not it would be the case?
Finally, is there any benefit in doing only chemo (which consist in daily pills but can be done at home hence less demanding)?
Did anyone had this dilemma and what was their choice/guidance? Any (recent) article/research paper?
For me it seems the most important question instead of increasing the life expectancy, is the state he will be in during/after the treatment.

Thanks for reading and any help would be more than welcome in this difficult moment

Interested in more discussions like this? Go to the Brain Tumor Support Group.

@lisamorris4272

Hi so Dad had the craniotomy 2 weeks ago today, they managed to remove it all. you wouldn't know, hes marvellous, like nothings happened. this week we went to see consultant and told it was GMB Grade 4 so the worst kind of brain cancer.
he is very optimistic and wont let this get in his way of living.. he didn't want to know the prognosis..
he starts radiotherapy 5 days a week for 6 weeks, soon, we don't have a date set yet.
so far things are going well. so happy Dad is thriving and hasn't changed.

How is Bill doing ?

Jump to this post

My 86 year old husband has GMB 4. Inoperable but stereotactic biopsy done on 10/16/23. He had to wait 5 weeks for the surgical site to heal before beginning radiation. Longer than we expected, but began chemotherapy simultaneously. The initial treatments were very tough, but he is doing well now, 7 months down the road. Chemotherapy is to continue beyond the typical 6 cycles because his tumor continues to shrink. No known prognosis at this point, but it’s clear he’s doing better than expected. Praying that your father has a great response to treatment!

REPLY

how about asking the dr these question?

REPLY
@nancyhafer

My partner Bill a 70 year old healthy man had a craniotomy October 3 to remove the glioblastoma stage 4 tumor and it was a success. Had some vision loss as the tumor had wrapped around the vision area. He was great after surgery. Walking, taking and seeing. Cognitively he has experienced some challenges and was told not to drive as his peripheral vision is bad. His incision healed well so was able to start 15 treatments of radiation and oral chemotherapy. Took a month off from treatment in December. Then started oral chemotherapy in January 5 days per month and every month since. He tolerated it well so dosage was increased in April . He is still tolerating it well. MRI’s so far have shown no progression. We have our 3rd MRI since the craniotomy next week. We have been traveling and he visits his grandkids in Denver every 8 weeks. Best wishes for your dad’s surgery. Keep me posted how he does.

Jump to this post

Hi how are things with Bill
my dad is doing so well.
completed course of radioitherapy, and now on chemo 5 days once a month, lastest scan was clear, hes to complete 6 months of chemo which ends next month then re-scan with 3 months off treatment .. then review.
i honestly cant believe how well he is. only problem is hes not able to drive, which he is still angry about!
hope Bill is well.
x

REPLY

Things are hopeful. In October 13 months after diagnosis the MRI showed no progression in the original resection but a new deep tumor had grown on the right side. He did 2 weeks of heavy radiation and then started Avastin through immunotherapy every2 weeks. Just had MRI and the new tumor shrunk and the resection area was stable still. So going to continue the course. Only side affect from immunotherapy is elevated blood pressure which we working on with more bp meds. He still goes to the gym…walks there😊 and looks healthy. He does feel like he is more easily distracted at times but he also is stressed with aging parent issues. He too is angry about no driving, but he is alive👍🏻 Thanks for asking!

REPLY
@kylebar

Thank you. It has been a struggle everyday. What makes it worse is I have very few friends and despite asking them for help in the form of a phone call or quick email from them maybe once a week, I get nothing. I have read so many accounts online where a good support group is needed to help deal with the grief. I thought I had that but I was fooled. I talk to a therapist three times a week so I have someone to talk to. Even he is surprised at how little support I have gotten from family and friends. It is a very lonely experience.

Jump to this post

Sorry for your loss... My husband (58 yrs old ) is going through stage 4 gbm and is unable to have the tumor removed since it is on his motor strip and speech.. he almost died from complications from a brain biopsy Feb 2024... . he is now on chemo pills and IV treatment.. MRI every 3 months.. last one showed tumor smaller and is stable... so at least that is something....I feel like my support from my family is lacking the communication and think our families are unsure how to talk about what happened.. idk ...I hope and pray my family and friends reach out to me.. maybe they are all afraid to show feelings,.... I will continue to keep you in my prayers.. stay strong...

REPLY
@michgiantwins00

Sorry for your loss... My husband (58 yrs old ) is going through stage 4 gbm and is unable to have the tumor removed since it is on his motor strip and speech.. he almost died from complications from a brain biopsy Feb 2024... . he is now on chemo pills and IV treatment.. MRI every 3 months.. last one showed tumor smaller and is stable... so at least that is something....I feel like my support from my family is lacking the communication and think our families are unsure how to talk about what happened.. idk ...I hope and pray my family and friends reach out to me.. maybe they are all afraid to show feelings,.... I will continue to keep you in my prayers.. stay strong...

Jump to this post

I wish you the best. 58 is young. I am sorry you both are going through it. It is such a horrible thing to deal with and I think you are correct. People either don’t know what to say or don’t want to face their own mortality. I cried all the time the first two years after he passed. I am somewhat better now as far as the crying goes. I still cry every day but much shorter outbursts now. I hope you try to enjoy every minute with him that you can. Don’t argue about things. Be as supportive as you can be. We had our arguments over the years like all couples do but after he was diagnosed I never got upset with him because it wasn’t going to help matters. I tried to be as cheerful as I could be with him every day.

I have a bunch of photos of him during our 25 years together but I don’t have many videos. I wish I had taken more videos of him. I took several during his time in rehab after the surgery but I wish I had taken more during our more happy times.

REPLY
@kylebar

I wish you the best. 58 is young. I am sorry you both are going through it. It is such a horrible thing to deal with and I think you are correct. People either don’t know what to say or don’t want to face their own mortality. I cried all the time the first two years after he passed. I am somewhat better now as far as the crying goes. I still cry every day but much shorter outbursts now. I hope you try to enjoy every minute with him that you can. Don’t argue about things. Be as supportive as you can be. We had our arguments over the years like all couples do but after he was diagnosed I never got upset with him because it wasn’t going to help matters. I tried to be as cheerful as I could be with him every day.

I have a bunch of photos of him during our 25 years together but I don’t have many videos. I wish I had taken more videos of him. I took several during his time in rehab after the surgery but I wish I had taken more during our more happy times.

Jump to this post

Thank you for the kind words.. I don’t argue anymore about anything with him and try to always cry not around him.. we have a 27 year old Son and 25 year old daughter with a 4 month old baby.. Monday Jan 27 we will be married 30 years .. I married him after 3 months of knowing him.. he’s the best thing that has ever happened to me.. 20 years in the military which I believe gave him this cancer.. I cherish everyday with him and don’t know what I will do without him around .. I am 48 so it’s going to be hard but I know I will get through it.. hopefully treatment will work and we have years together… never in a million years did I think this would happen.. life is just strange sometimes..

REPLY

It is strange. I never thought I would go through what I did either. It is hard not having him around. The loneliness is the worst part. I have had others tell me the same thing. And I thought I knew what grief was until he died. I have lost both parents and some friends and coworkers over the years. All of that grief combined doesn’t compare to this grief at all.

REPLY
Please sign in or register to post a reply.