In my case with bronchiectasis only, over time I have lost some weight. Not enough weight to cause concern from my PCP. My clothes fit better and I am happy about that. Nonetheless, if/when I get an exacerbation it's easy to drop weight (and muscle). Making sure I eat enough (including lean protein) is a daily essential for me. Plus, watching GERD triggers. I'm currently experimenting with the Acid Watcher Diet for GERD/reflux. In summary, it's eating alkaline rather than acidic foods, plus a 1lb of veggies and 1/2 lb of fruits per day. Very healthy but I need to make sure I get enough calories.

Michele McDonald (sp)?) of NJH presented on weight loss with bronchiectasis and MAC. It was truly informative. It's on this site somewhere. She encouraged caloric density (nut butters, nuts, etc). She also mentioned a drug regimen, which has been quite successful for managing weight loss. I believe it's a low dose anti depressive along with an ADHD medication. The anti depressive works to increase appetite and the ADHD drug keeps one moving and active.