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Hi, @sarnm, and welcome to Mayo Clinic Connect. I think that members like @efexnot @efexfreeforever @ladislara @brightwings @nanke99 and @gwenaloveseveryone2 may have some thoughts to share about how the path tapering off venlafaxine (Effexor) goes and any suggestions they might have.

How has this week on 150 mg gone, overall for you, with the taper down?

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Replies to "Hi, @sarnm, and welcome to Mayo Clinic Connect. I think that members like @efexnot @efexfreeforever @ladislara..."

Thanks to all for the quick feedback.So far, nothing too bad. I did have an angry episode one night but self medicated with Xanax and wine. I would like to get off those as well.  Does anyone have insight into how medical marijuana might facilitate the process Effexor withdrawal? I used to work somewhere that drug tested, so that was not an option, but I’m retired now.

@sarnm — Really glad to hear you've experienced nothing too bad with the taper off of venlafaxine (Effexor) this week.

You mentioned medical marijuana and a question of how it might facilitate the taper off of venlafaxine (Effexor).

Here is a Mayo Clinic video on the general topic of medical marijuana, if you're interested.

When is your next taper down?

@sarnm I live in Washington State and marijuana is legal for recreational and I'm using it to help me wean off Effexor. I've gotten down from 225 mg to 37.5 mg in a short time frame. I take 5 mgs THC about twice a week. For comparison I think a joint has around 500 mgs THC. It doesn't make me high, just sleepy so I have it at night. My only Effexor weaning side effect is occasional foggy head. This is a HUGE improvement over the other times trying to get off. I actually feel less anxiety and depression than I did with the high dose of Effexor! I never thought I'd say this but I wish everyone could have legal access to marijuana!!