I have been taking hydroxychlorequine for at least a year. At first I was on a dose of two 100 mg(?) per day. My main side effect was horrific, gorey nightmares. I went down to one tablet per day and the nightmares went away. I noticed an improvement in my dry mouth almost right away which is why I persisted. The main symptom I am dealing with is dry eye. I am now on Imuran along with the hydroxychorequine and seem to be stabilizing, although I will probably never see out of my left eye again.