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Zoloft causing long term IBS

Posted by wishingonastar @wishingonastar, Jan 27, 2024

Anybody had Zoloft trigger IBS that won't go away, even when stop Zoloft? Any suggestions? Did anyone at Mayo Clinic help with this?

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cyncha | @cyncha | 2 days ago

I was diagnosed with microscopic colitis about 3 years ago. Budesonide helped cause remission for about a year, but since then I have had bouts of the runs and have unable to get off the drug. Then, reading about sertraline's effect on the digestive system over Christmas, I vowed to never take Sertraline again without having breakfast first. So far, it's like a miracle has happened. I'm in the process of trying to wean myself off budesonide again and I'm not having any close calls! Happiness! It's only been 4 weeks but I couldn't wait to share this with you!

REPLY
1 reply
wishingonastar | @wishingonastar | 2 days ago
In reply to @lunagaialove "I have had Zoloft activated IBS for the last 4 years, after taking it for 6..." + (show)
@lunagaialove

I have had Zoloft activated IBS for the last 4 years, after taking it for 6 weeks.
Afterwards I experienced 8 months of nausea and IBS, winding up in the ER with a severe electrolyte imbalance and was in the hospital for 2 1/2 weeks.
In those 8 months, whenever I spoke to my doctor about my severe bowel problems after taking Zoloft, they brushed my symptoms off as anxiety.
Loooong story short, I have found relief with low dose Nortryptiline.
However it’s not a resolution, I’ve tried to go off of it, but as soon as I get a little stressed about something it flares right up.
I will investigate further now that I know I’m not alone 🙏

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You are not alone! My relative with this problem has similar story. Has tried Budesonide even though colonoscopy did not diagnose microscopic colitis. Definitely helped but not resolved. Let's stay in touch to compare notes. Will mention the low dose Nortyptiline. I wonder if a lawyer would investigate this as a class action matter.

REPLY
wishingonastar | @wishingonastar | 2 days ago
In reply to @cyncha "I was diagnosed with microscopic colitis about 3 years ago. Budesonide helped cause remission for about..." + (show)
@cyncha

I was diagnosed with microscopic colitis about 3 years ago. Budesonide helped cause remission for about a year, but since then I have had bouts of the runs and have unable to get off the drug. Then, reading about sertraline's effect on the digestive system over Christmas, I vowed to never take Sertraline again without having breakfast first. So far, it's like a miracle has happened. I'm in the process of trying to wean myself off budesonide again and I'm not having any close calls! Happiness! It's only been 4 weeks but I couldn't wait to share this with you!

Jump to this post

So happy to hear this good news! Please keep us posted.

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