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Is there any successful story ?

MAC & Bronchiectasis | Last Active: 1 hour ago | Replies (13)
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@helen1000

Per this news there is a better drug than ethembutol.
https://www.sciencedirect.com/science/article/abs/pii/S0040402024004800
New antibiotics against MAC/MAI

- Total syntheses of mavintramycin A and its structural analog, cytosaminomycin C, and evaluation of their antibacterial activities against Mycobacterium avium and Mycobacterium intracellulare

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Replies to "Per this news there is a better drug than ethembutol. https://www.sciencedirect.com/science/article/abs/pii/S0040402024004800 New antibiotics against MAC/MAI -..."
Sue, Volunteer Mentor | @sueinmn | 14 hours ago

The news here is that they have found so far, mavintramycin A works on a certain strain of NTM in silkworms, and on M. avium implanted in mice.
https://journals.asm.org/doi/10.1128/aac.00917-23
These are very preliminary steps that look promising, but typically at this stage we are 5 - 10 years from an new therapy - let's hope it works out!

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