A study completed a few months ago, called the Patch study. It showed that taking estrogen in the right amount, using a patch, replaces Lupron and reduces the side effects. It has the exact same effect as Lupron on your testosterone. It also will give you back some of your desire for intimacy, which Lupron takes away

Using estradiol patches works great to replace Lupron. Talk to your doctor about this. There’s no reason you should be having Lupron as well, Maybe you just need slightly more estradiol.