Hi, again you brave people. I feel like we are all going into battle against this hideous drug. I weaned down to 37.5 on the 4th and 3 days later I had to go back up to 75. I was so sick I couldn't hold my head up. The headaches and nausea, vomiting and vertigo were very severe. I called my P-Doc and she said to go back on the 75 for another week and try again. So today I started the 37.5 again. I weaned off of Buspirone with no problem at all and did well coming off of the Effexor too until I reached this 37.5 dose. We have been decreasing very slowly. I've been on Effexor for over 25 years and other psych drugs for Bi-Polar disorder and now I have kidney disease..coincidence? I don't know but my doctor said these drugs are hard on the kidneys. Strangely I haven't experienced any emotional problems at all. All physical. Anyway, here I go again. Wish me luck. I hope I won't be back in another week saying I couldn't do it again.xxoo