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Support For Those Quitting Prolia
Osteoporosis & Bone Health | Last Active: Jan 20 7:30pm | Replies (171)Comment receiving replies
That is very true, windyshores. If using Reclast to relay off Prolia, it is better to time the infusion as Reclast is a 1-yr dosage and using it at the wrong time would render it much less effective. I have read that for Alendronate, it is not necessary as Alendronate is a weekly dosage so timing is less of an issue. That is unless the rebound is somehow delayed for more than 18 months after the last Prolia injection. Usually however, the rebound may start to happen as soon as 6 months after the last Prolia. In any case, I didn't even find a doctor who knew how to order the BTM test until 3 months after i had started on Alendronate. And i didn't come across any guidance on what to do if one encounters low CTX during the relay stage
Btw, how long has it been since your last result of 145 and what is your target level to do the next infusion?
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My 145 CTX was last month. I asked for it before doing my next infusion. My doctor thought it reflected suppression from a recent infusion and I reminded him that I had not had the one scheduled.
I figured things would be different with alendronate in terms of timing since it is weekly. So the issue isn't effectiveness, as it is with Reclast, if done too early. But the issue might be over-suppression of the Prolia is still keeping the CTX down. You are probably fine: I think McCormick is referring to over-suppression over time.
Doctors all vary so much in how they approach bone marker testing. Hope you get answers from your MD!