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Effects of HRT: Alone, in Combination or Sequencing

Osteoporosis & Bone Health | Last Active: 45 minutes ago | Replies (33)
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@kisu

Thanks, Mayblin for replying. Would you say he has more concerns about testosterone than estrogen? I wonder why he thought a small amount of testosterone would be bad. There is so much conflicting information from doctor to doctor. It's like you must know more than your doctor and take your health into your own hands.
I have CAD, a CAC of 79, and osteopenia. I asked my Cardiologist if it was ok to use my 0.05 estradiol patch for my osteopenia. He said, "Sure, but it causes breast cancer." I started to say there was new information, but he interrupted me and doubled down, "It causes breast cancer." I also told him I'm also using 4mg of topical testosterone cream a day, and he said fine. My dilemma is can I trust him at all because he told me estrogen causes breast cancer?

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Replies to "Thanks, Mayblin for replying. Would you say he has more concerns about testosterone than estrogen? I..."
mayblin | @mayblin | 1 day ago

I was in disbelief that my regular cardiologist approved my estrogen use the same day via inter-department message to my obgyn without seeing me. Now thinking back, he probably knew my cvd risk well enough to give the approval right away. Not fully sure at the time, I went for a second opinion but testosterone use wasn't in my plan. This second cardiologist at a different institution went through all my labs/tests in the past and didn't hesitate to give a green light, although she set a new target of LDL-c below 55 and HbA1c at normal level (I was borderline prediabetic). She was the one mentioning "stay away from testosterone", which I think was based on my existing cad but I didn't ask further. Now I'm curious and will ask her at next appointment.

The risk for breast cancer probably is still derived from WHI, about 0.8 more cases per 1000, although data were based on CEE and MPA. The mortality rate did not increase because of it as data showed. I had obgyns assessing my bc risk. Even with a low risk profile, the decision was still a hard one. I've discussed with family members with a plan in place should bc happen to me.

Hope you get your risk vs benefit sorted out soon. Maybe seeking an opinion from a obgyn for breast cancer risk?

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