← Return to Looking ahead after Tymlos: Reclast, Evenity or HRT?

Discussion
Comment receiving replies
@gently

kaa1, the decrease in forearm density may not be significant for fracture risk. "[M]eta-analysis showed a neutral effect on forearm and wrist fractures overall" from the loss of cortical bone density with anabolic drugs I'm not that fond of meta-analysis, but here's the link. https://www.sciencedirect.com/science/article/pii/S8756328218303600
There is speculation that the decrease in cortical bone density with anabolic medications for osteoporosis is the effect of initial bone remodeling. Nine months would be too soon to see the end density results with Tymlos.
In addition, bone strength isn't measured by density alone. I have the vague idea that your wrists might be at greater risk, but can't remember any links.

Jump to this post


Replies to "kaa1, the decrease in forearm density may not be significant for fracture risk. "[M]eta-analysis showed a..."

Thank you for your reply. I will do some research.