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Support For Those Quitting Prolia

Osteoporosis & Bone Health | Last Active: Jan 20 7:30pm | Replies (171)

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@windyshores

@formisc McCormick also addresses CTX being too low. He says in his book that we should wait until the CTX rises enough after Prolia, before doing Reclast, for example. And anecdotally on this foruum people have said that a CTX too low can mean mircrofractures don't' heal, hence the atypical fracture- again according to McCormick.

You seem to be dealing with medications already. In my experience PCP's don't know that much about osteoporosis treatment. I strongly suggest an endocrinologist. You don't have to do what they say. And also reading and watching videos to be fully informed. This forum is all patients sharing experiences but if noone has your exact experience, it would be good to talk to an endo (and/or McCormick).

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Replies to "@formisc McCormick also addresses CTX being too low. He says in his book that we should..."

@formisc just found this regarding CTX being too low with more risk for jaw necrosis. Mine is 145 and I am delaying my infusion. :

"It measures the C-terminal telopeptide (CTX) value, which depicts the level of octapeptide fragment released due to osteoclastic bone resorption from type I bone collagen.[36] Its levels are related to the number of osteonecrotic lesions, stage of disease, and bone turnover index.[37] A lower value represents a high-risk patient with suppressed bone turnover and reduced healing capacity. C-terminal telopeptide less than 100 pg/ml equals high risk, 100 to 150 pg/ml equals moderate risk, and greater than 150 pg/ml equals minimal or no risk."