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DiscussionEstradiol For vaginal atrophy after breast cancer. Is it safe?
Breast Cancer | Last Active: Jan 20 10:01am | Replies (63)Comment receiving replies
Replies to "This is amazing…but I do question it. Maybe I don’t understand how that estrogen % is..."
From my research, I believe there are three naturally-occuring types of estrogen that circulate in your body: estradiol, estriol, and estrone. Estradiol has been used for years for vaginal dryness (e-string, Estrace, Vagifem, etc.) and can be either pharmacy-ordered or compounded (bio-identical). About 10 years ago I used a compounded vaginal cream of estriol, as it's the weakest estrogen but my oncologist disapproved of it so I stopped but it's back in favor again now. Ugh, sometimes I think it's just a CYA situation for doctors to advise against it, which is why the new study is so important because they can show some research that shows no ill effects. I put the link in a different response, but here it is again (just the abstract as the full article is behind a paywall) taken from the American Journal of Obstetrics and Gynecology:
https://www.ajog.org/article/S0002-9378(24)01126-8/abstract
It’s all ever changing