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PMR and Pulmonary Embolisms

Polymyalgia Rheumatica (PMR) | Last Active: Jan 22 12:10pm | Replies (10)

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@megz

I've been on Eliquis/Apixaban for 9mths, starting just after my first PMR flare while reducing to 6.5/6mg of prednisone. I got a large DVT clot in my leg just after the flare, which I put down to the increased inflammation and/or the sudden rise in prednisone dose because of the flare.

Start dose of Eliquis was 10mg twice a day, reduced to 5mg twice a day, then reduced to the maintenance dose of 2.5mg twice a day after 3 months. Been on the maintenance dose for 6mths now. I have a doppler ultrasound tomorrow to see if the clotting has cleared and I can stop the Eliquis.

With clotting being a higher risk while on prednisone, especially for those of us with a history of clotting problems of various kinds, the diet should be checked for high intake of vitamin K1 which increases clotting. Having checked what I eat, I've found the two handsful of arugula/rocket I eat every day in salad is very high in K1, so as much as I love it, it has to go.

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Replies to "I've been on Eliquis/Apixaban for 9mths, starting just after my first PMR flare while reducing to..."

The doppler ultrasound results are back and the extensive right leg clotting from 9mths ago has cleared while taking apixaban. My doctors say I should keep taking apixaban 2.5mg twice a day for a further 6mths due to some "old clotting" still there, and with the higher risk of rebound clotting if I stop the apixaban while taking prednisolone. Not happy, I would have liked to stop the apixaban, but their explanation appears sound, so I'll continue on with it.