Hi @rashida ONJ is short for OsteoNecrosis of the Jaw; AFF is short for Atypical Femur Fracture. They are very rare in occurrence and usually happen in association with high dose and/or very long term treatment of an antiresorptive. Sometimes patients' underlying conditions such as cancer, oral health have something to do with the occurrence. I'm going off topic, my apologies.

Windyshores and gently had summarized the answers to the original post very well.