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DiscussionWhat are some situations where Prolia is a very good choice?
Osteoporosis & Bone Health | Last Active: Jan 20 7:22pm | Replies (23)Comment receiving replies
Replies to "Jan. 18, 2025 thank you @mayblin for bringing to our attention and posting the link to..."
Hi @bevlevvancouverbc my intention of posting that link is to show the study demonstrated evenity's effect on bmd after 12mo prolia (2shots) were attenuated, although no statistical analysis due to the small sized study. What the study did not show in any way is what role evenity has, if any, in preventing rebound effect upon cessation of prolia. I am not really bothered by the funding sources or some of the authors being consultants to some drug companies. Clinical studies are expensive to conduct and in need of top notch scientists and researchers who in real life often wear many hats. Randomized, double blind clinical trials are said to be the best scientific studies out there. This phase 2 study was randomized although thr number of participants was small. However, if we need more peace of mind regarding Evenity itself, its phase 3 study is more telling - a randomized, double blind clinical trial with over 7000 participants. Results had statistical power.
With regard to the sequencing of prolia -> evenity, more studies are needed.