Neuropathy associated with Mounjaro use

Posted by melindaheim @melindaheim, Oct 8, 2024

Has anyone had the experience of new or increased neuropathy associated with Mounjaro use?

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Hello,
I started Mounjaro 2.5 the week of new years 2025. Within a day of the 1st dose, I had restless sleep, muscle spasms, pins and needless in hands and feet and numbness in both hands and feet. At first I was thinking it was my pillow so I bought 3 different ones and flipped my mattress. But it was getting worse. I was thinking part was from my herniated disc's and my distal bicep tendon tear. But these symptoms just didn't add up to the occasional nerve compression pain i experienced before. This was absolutely continuous. I also noticed on my normal daily routines my muscles were so weak and tired. I had to take a lot of breaks. The day before my 2 injection, called my Dr and because neuropathy pain was not on any documentation he wanted me to take a second dose and see if everything subsides. It didn't. The pain only got worse and the exhaustion set in from lack of sleep. I called my doctor prior to the 3rd dose to give and update. I had not heard back and Due to my sugar levels I reluctantly took a 3rd dose. I called his office again and I refuse to take my last dose. I can't do it anymore. I'm hoping to not only share my story, shed light on a side effect but I'm also hoping to get answers as of reprieve status. It's only been 1 day but I am hoping it subsides.

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Sorry you are experiencing this. I hope you get better. I worry how many other side effects will surface with this relatively new "wonder" drug.

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I have been on mounjaro 5 mg and 7.5 mg for over a year for insulin resistance/diabetes. I have started last April 2023 with weakness/tingling/joint pain from waist down. I have been to numerous doctors from neurologist, rheumatologist, orthopedic doctor and had many tests done to get proper diagnosis to no avail. I have financial decided to stop mounjaro 3 weeks ago and today first time in months my severe leg pain and weakness feels much better. I am able to walk without needing to rest every few steps. Still very stiff but without severe, burning and achy legs. I am still in shock that this could be mounjaro.

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HI. YES! But NO! LOL I would'nt call it nueropthay however, i do have the muscle soreness, the joint soreness, the headache, the dry mouth and that tingling feeling on my skin. My body gets so sore, i can barely function, I have googled but your right, no one has recognized it other than some REDDIT postings where others have experienced the same.

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