I totally agree with you about it being a life-long disease. I didn't have it until I went through my divorce and the loss of my son. I think that once the chemicals in your brain are shaken up, there's a slim chance that they will ever return to "normal", whatever that is these days. The reason I wanted to wean off of the Effexor after 14 years of taking it is because I am experiencing critical physical symptoms that, according to the Effexor warning label, are caused by long term use of this drug. I was suicidal after my divorce....had been married to my hs sweetheart for almost 30 years and my son was in Iraq on his second of his third tour with the USMC. I had a nervous break down. In the meantime, I lost the best job I ever had in my life; one that would ensure financial stability through the divorce. I had to leave the dream home we had built ten years before, my son came home from Iraq very depressed and I worried to death about him. Then when he had to deploy for a third time, I tanked again and had to be hospitalized. When my son passed away in 2012, I went on disability because I couldn't deal with the grief of losing my 29 year old son. I really think my mind and body have never healed from one tragedy before the next struck. The Effexor caused me horrendous brain fog to the point I could barely take care of myself and my dog. I literally didn't know where I was half the time. I couldn't go to the grocery store, do laundry, cook for myself, dishes....nothing. My house went to complete hell. I slept probably 16 or 18 hours a day. I gained 50 pounds in about 4 months which sent my bp skyrocketing....my doctor increased the Effexor because of my critical state which only made my bp worse. I just turned 60 and am beginning to truly worry about my physical health as it relates to the drugs I am ingesting....Please, please, please, anyone who is taking antidepressants READ THE WARNING LABEL EVERY SINGLE TIME YOU GET A REFILL. Side effects change and the date of the last update is on the BACK page in teeny tiny little numbers in the left hand corner of the warnings instead of in big, black bold letters on the FRONT. I am convinced that the cocktail of antidepressants the VA gave my son caused his suicide. Today, we are losing 20-30 Veterans a DAY by their own hand. 90% of it is because of the medication that the VA prescribes. It is absolutely criminal. Big pharma contracts with the government, gets these men and women addicted and then they die by their own hand. I think it's cheaper for the government to buy the drugs than treat them medically for their problems. That's another chapter in the book, though, and I won't bore you with statistics most of you don't even care about.