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Has anyone DAO (diamine oxidase) deficiency?

Epilepsy & Seizures | Last Active: 4 hours ago | Replies (3)

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@santosha

@lisalucier
Hi Lisa, Good Morning
Do you know of any article or study by the Mayo Clinic regarding the relationship between histamine/ DAO Deficiency and seizures? And also what are the AEDs that can cause DAO deficiency?
Here I share a study from 2012 that I have found through searching more about this subject.
https://pmc.ncbi.nlm.nih.gov/articles/PMC3514756/#:~:text=Histamine%20is%20considered%20to%20be,et%20al.%2C%202004)
Yesterday, I was at my gastro and came out of this appointment with her very disappointed. She said I am not a specialist in epilepsy and AEDs. Initially, she said she was not aware that AED could cause DAO deficiency, but after making quick searches she found that carbamazepine and topiramate can cause DAO deficiency. Clearly, she did not prepare for this appointment.
She said that Keppra can cause all those gastrointestinal problems I am having and recommended I see a nutritionist to start a diet to hold on better with Keppra and feel a bit better.
Thank you!
Chris (@santosha)

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Replies to "@lisalucier Hi Lisa, Good Morning Do you know of any article or study by the Mayo..."

Hi, @santosha - I don't off the top of my head, but I can look into it.

Sorry to hear about the disappointing appointment.