I'm already trying to get off of Venlafaxine, it really only subsides the anxiety minimally, I am only on 37.5 and have only been on it since March of last year. I've tried to go up to 75mg a few times, each time trying, my symptoms just got worse. So, I'm just going to smoking Marijuana, which actually helps me tremendously. I have my Medical card and there are about 7 different types that are great for anxiety and depressed, so much better than tsken pills. In my opinion.