← Return to Nausea taking 2.4 mg of wegovy. No issues before

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@wynnejo

I've been on the 1.7 for 3 months. I ALWAYS vomit & stay in bed the day after the shot. Dr appointment tomorrow & will discuss with him. I also stay Extremely Tired ALL THE TIME. I'm considering going off Wegovy. I've lost 32 lbs since July.

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Replies to "I've been on the 1.7 for 3 months. I ALWAYS vomit & stay in bed the..."

@wynnejo
At least you did lose some weight on it.

I agree if were me I would come off also. That is way to much side affect that I could deal with.

Does your doctor think a different maker would have less side effect. I don't think I have the right name but mine mentioned enbound (spell) or something like that saying was more toward the signals to brain versus the full feelings with less side effects.

I am trying hard to do it on my own.
Good luck and if you don't mind let me know what your doctor says and if recommends something different.

For what it's worth -- one person's experience only -- I titrated very slowly up (a lot slower than the studies called for) on tirzepatide (zepbound), and then titrated slowly down after I hit my goal weight, and never lost the side effects. Which to be fair, never included vomiting regularly, so I'm stunned you've kept it up, which is amazing dedication.

The worst side effect for me (among many) was my turbocharged migraines. I've had migraines for pushing 60 years now, but I had never gotten to the point where I was taking three preventives and my rescue meds stopped working.

Finally switched to semaglutide (ozempic, which is the same as wegovy but uses a different dispenser) about a month ago. I'm titrating up. Interestingly, I'm hitting some side effects, but they are different side effects. (My migraines have largely stopped, for example, while the light-headedness is a lot worse. After discussing it with my doctor, I stopped simvastatin, and it's made a substantial difference to the light-headedness. In fact, I've now got an entire plan in the works to stop or change almost every other drug I'm on, several weeks apart, to see what happens, since I really don't want to stop the GLP-1 RAs.)

At any rate, you might consider either titrating down on the wegovy to gradually lower doses, or switching to zepbound (tirzepatide), or do the first one followed by the second one. Unfortunately, and for obvious commercial reasons, no one has actually done a study to provide guidance for any of that. Therefore, it's all a judgment call. I titrated all the way down to the lowest dose of zepbound, and then started on the lowest dose of ozempic. No one actually knows whether this is the best approach, but it seemed to make sense to me.

Finally, if you do want to try switching, you might consider asking for a Mounjaro Kwikpen instead of Zepbound if you are not constrained by your insurance plan. This is because the Kwikpen allows you to fine-tune your dosages, just like the Ozempic multi-pen does (and which Mounjaro and Zepbound don't). If you want more on that, just let me know. Be aware that both manufacturers strongly oppose doing that, but I'm doing it anyway.

@wynnejo
How did the doctor's appointment go? Did he suggest any changes?