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Prostate Biopsy Complication

Prostate Cancer | Last Active: 4 days ago | Replies (32)
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@heavyphil

New EPICAPTURE TEST. A small Dublin based biotech co (TRIB?) announced that they have a new urine test that is almost 100% effective in diagnosing aggressive (Gleason 8 or higher) prostate cancer.
It is used along with PSA tests mostly in the gray area of 4-10. It shows methylated DNA in the urine which is associated with more aggressive cancers. It’s a good option in AS to avoid repeated biopsies.
There are other urine tests out there but supposedly this is the first one that takes into account other factors - and the test was matched up with an actual biopsies and showed a high rate of predictability.
This is great news and offers men another piece of data they can use to make a more informed decision about whether to re-biopsy or not.

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Replies to "New EPICAPTURE TEST. A small Dublin based biotech co (TRIB?) announced that they have a new..."
clandeboye1 | @clandeboye1 | Jan 13 8:00am

Where did you read this announcement article ?

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handera | @handera | Jan 13 9:20am

Thanks for this information! I've been researching various liquid biopsy alternatives for AS patients and I had not seen this one. Apparently, Trinity Biotech bought the start-up company who invented the Epicapture Test in October 2024 and has announced plans to commercialize in the US...however, no date has been set....

Read where this particular test only has 5% false positives....that's amazing when one considers that the false positives for the standard PSA blood test is 46.6%, according to a 2022 study….imagine if a company were attempting to bring such a test to market in 2025....that type of test wouldn't even make it to first base after an initial screening of possible solutions.
https://pmc.ncbi.nlm.nih.gov/articles/PMC9818944/
In 2021, ~60% of low risk PCa men have chosen AS, as compared to only ~26% in 2014. This means that the market for a noninvasive biopsy method has grown exponentially; therefore, I believe it's just a matter of time (sooner rather than later) that such a liquid biopsy replacement test will be made available...there is a large and growing market and we all know what the means for the medical industry....

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