Thank you @windyshores for the detailed information. I think because I'm premenopausal, the oncologist was looking specifically at the cohort of premenopausal women in the TailorX study, and factored in some of my specifics, like the larger tumors. It's really my decision whether or not to do chemo, and then I would have radiation and endocrine therapy. I am leaning towards doing it to have the peace of mind. I'm 45 so that recurrence risk would only be my mid 50s so to me, cutting the risk in half would be very reassuring. (On the other hand, I really do not want to experience everything that comes with chemo!) I really appreciate youre response.