@ling and @mmahlik Many people in this group use either albuterol or levalbuterol nebs daily for a long time. These have been the short-acting beta-agonist drug of choice for opening airways incases of Asthma, Bronchiectasis and other lung disorders for many years, along with Salmeterol.

Three years ago, it was suggested to me, that using the same medication in an inhaler may be as effective for opening airways before 7% saline and airway clearance. I still used the nebulized version during an exacerbation. It worked for me, reducing the bronchospasms I sometimes got from nebulized levalbuterol. I believe some others here also use this method - it cuts about 15 minutes off each airway clearance session.

More recently, my pulmonologist switched me to a generic version of Symbicort, a combination long-acting beta-agonist and inhaled corticosteroid. (formoterol/budesonide) She explained it is the current best protocol for treating long-term moderate asthma, and that the budesonide is less likely to suppress the immune response to bacteria than prednisone.

But the answer to your original question about daily use is -I'm sure there are side effects, but it is prescribed for daily use world-wide and has been for over 40 years and it has saved countless lives (I lost friends in school, my great-grandfather and a 50 year-old neighbor to untreated asthma.)