This is my personal opinion on the mchc …for me it does not upset my stomach. That study was years ago as was the woman’s study on hrt which has since been discounted. My numbers have improved but I feel it is a combination of supplements, weightlifting, bioidentical hormones replacement for over 20 years. It is a personal choice. I tried the algae form years ago and had terrible stomach upset but others have wonderful results. Best of luck to all on this journey. Xo