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Decipher Results and Outcomes: Anyone had similar?
Prostate Cancer | Last Active: Jan 13 7:42am | Replies (33)Comment receiving replies
So this tells me that there is little science in these scores unless the slides are so obviously abnormal. I had two biopsies with first being interpreted as 3+4 and then read at Hopkins giving them a 3+3. A second biopsy a year later was 3+3 verified using AI. I get a third biopsy on Monday afternoon. My decipher on the first biopsy came at .37 low risk.
Replies to "So this tells me that there is little science in these scores unless the slides are..."
Why not use PSE or EpiCaPture tests? They would show the presence of aggressive cancer needing treatment.
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@imbimbo
I know you replied to @hoover58. But I wanted to give you my personal experience.
The expertise, experience, training, etc. of your urologist and pathologist has a great impact on accuracy of biopsies and Gleason scores. I would not discount the Gleason scores at all. Just know they are subjective to the expertise and experience of who is reading them.
The do give a diagnosis to work with. At that point you need to decide if want second or third opinions. Most of us suggest doing that. Then you will get more than one opinion on your diagnosis and treatment options. If they come back with same, good, if not then make decisions.
What I and a lot of others did and now suggest is at test like Decipher test which is a genetic test much more objective than the subjective Gleason Score.
It seems your Decipher test were very close to each other. Some pathologist are going to be more on doing a highest number probability than leaning toward a lower number probability.
I think your Decipher helped you with the low risk diagnosis. The is what happened to me also. Original Gleason was 3+4=7 (worse biopsy others 3+3=6) and intermediate risk. My decipher came back low risk. My R/O at Mayo urologist, Mayo R/O, R/O at UFHPTI, and Mayop PCP all agreed with Decipher results and the recommendation of radiation only treatment.