I usually go with "Been better, been worse" when asked how I am, then leave it up to them to ask to hear more (or not.) When my husband occasionally reaches his limit with my medical talk, he just honestly says "I don't have the bandwidth right now, can we talk about this later?" I appreciate that. It's a good reminder that, while I might be laser-focused on research and trying to find answers for my health issues, there are other things in life to talk about. 🙂