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Decipher Results and Outcomes: Anyone had similar?

Prostate Cancer | Last Active: Jan 13 7:42am | Replies (33)

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@hoover58

I wouldn't stop with a second opinion. My first biopsy was 3+4 at Vanderbilt Medical Center, 4+3 at Johns Hopkins, and 4+4 at MD Anderson. Those were all from the same set of slides.

A gleason score is just someone's opinion, and it is very subjective.

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Replies to "I wouldn't stop with a second opinion. My first biopsy was 3+4 at Vanderbilt Medical Center,..."

I agree 100% I to had different opinions. I took the spread of my cancer as did my doctors as very aggressive and have pursued treatment accordingly.

@hoover58
Good information. That is the feedback I got that Gleason Score was subjective from the specialist looking at it. It really is looking at normal cells to abnormal ones and how much the differ.

It is why I always post consider Decipher test as more objective and genetic test.

So this tells me that there is little science in these scores unless the slides are so obviously abnormal. I had two biopsies with first being interpreted as 3+4 and then read at Hopkins giving them a 3+3. A second biopsy a year later was 3+3 verified using AI. I get a third biopsy on Monday afternoon. My decipher on the first biopsy came at .37 low risk.