I have previously researched & looked at feedback from multiple sources. It is clear people react very differently as individuals. Both in how high an mg dose of Anti-depressant they can tolerate. And , how quickly they can then titrate off of them. It seem that , as with me & effexor / Venlafaxine, dropping down from 75 mg to 37.5 mg can be done by many people in quite a short timeline. BUT, it is commonplace that then dropping down from 37.5 to 0, has to be done MUCH more slowly. I have seen many cases reported, where withdrawal symptoms get much more severe, post the 37.5 mg dose. Having said that, I am in the lowish % of people that are hyper sensitive to ANY Anti-depressant. So, the hyper slow dropping down from 37.5 took a long time to be able for me to cope with the withdrawal side effects, at each stage of reduction. At the extreme opposite, Some people can stop & start taking any Anti-depressants at will, with very little adverse effects.