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Did you choose active surveillance? Why was it a good choice?
Prostate Cancer | Last Active: 19 hours ago | Replies (42)Comment receiving replies
I have a question about active surveillance. I was given that option. But as jeffmarc has pointed out my 3+3 gleason 6 should be AS. But why would you wait on a 3+4. What are we waiting on. To get worse? Reduce the inevitable side effects? Would there be any likelihood its not going to get worse.
Replies to "I have a question about active surveillance. I was given that option. But as jeffmarc has..."
Began AS in October 2023, after being diagnosed with low volume 3+4 and Decipher score of 0.22.
After an initial mpMRI showed PIRADS 3, 4 & 5 lesions, only one reduced T2 & DWI/ADC signal lesion (the original PIRADS 5) could be observed in my 12 month follow-up mpMRI.
So....yes...a 3+4 diagnosis (with low decipher score) can regress. I personally believe it may be due to my 90 minute/week vigorous aerobic exercise regiment, which I started upon PCa diagnosis...but who knows for sure...clinical studies & RCT's would suggest that could be the case.
https://jamanetwork.com/journals/jamaoncology/fullarticle/2783273#google_vignette
https://www.health.harvard.edu/mens-health/exercise-may-slow-prostate-cancer-growth
Recently, CoE institutions (UCSF & UCLA & John Hopkins) have all completed independent studies suggesting a healthy diet may also help slow PCa progression...but who knows for sure...
One thing I do know for sure is that my VO2 Max has increased from 40 to 47 and I have lost 25 lbs, since I was diagnosed.
- https://www.ucsf.edu/news/2024/05/427571/prostate-cancer-study-more-health-benefits-plant-based-diet
- https://www.uclahealth.org/news/release/low-omega-6-omega-3-rich-diet-and-fish-oil-may-slow-prostate
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Follow your medical experts . Your Urologist should follow you closely on AS . I have a friend currently on active surveillance , for 7 years , with G6 and Gleason 3 + 4 = 7 . He just turned 60 last June . He has keept abreast of the emerging new advances over the years -- He has options today he did not have 7 years ago . He is currently considering NanoKnife should he decide , in concert with his Urologist , to discontinue his AS . He is also not opposed to other Focal Therapies as they advance .
You not have read my thread on my biopsy experience . Biopsy 1 A Transperineal MRI Fusion Biopsy 5 Cores - ALL Negative . Clearly in conflict with my MRI RADS 5 Score . My 2nd Biopsy a 16 Core with 6 cores in the same target area as Biopsy 1 . The 6 cores in the same target area as Biopsy 1 came back Gleason 3 + 3 = 6 .
A 2nd opinion on my G6 came back : ALL 6 CORES Gleason 3 + 4 = 7
A 3rd opinion : 4 Cores G6 2 Cores Gleason 3 + 4 = 7 . All other other cores of the 16 came back negative .
I hope this reinforces my advice . Get a 2nd or 3rd opinion of your biopsy slides .