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Anyone participate in RMC9805 and RMC6236 clinical trials?

Pancreatic Cancer | Last Active: 1 day ago | Replies (20)
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@mimimmx

Yes. I am on the RMC trial combo for 6236/9805. I just completed my 4th cycle (every cycle is 3 weeks). I have had an excellent early response with the 1.6cm lesion in my liver and 1.5 cm lesion in my abdomen near my left adrenal gland are too small to measure as of yesterday’s CT scan. My doctor said this is an unusually good response. The side effects are challenging (facial rash that bleeds, scalp sores, mouth sores, diarrhea) but not nearly as difficult as the folfirinox side effects. Doctor has made clear it is not a cure but could extend my life by some time. Let me know if I can answer any other questions.

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Replies to "Yes. I am on the RMC trial combo for 6236/9805. I just completed my 4th cycle..."
gnest | @gnest | Jan 8 7:21pm

Thank you @mimimmx for your response and sharing your experience. I am glad the treatment works for you. It gives us some hope.
We understand it is not a cure. Hopefully it will be a long-term treatment.
We are waiting for a screening eligibility for this clinical trail.

My mom worries a lot about facial rash. Is there any cream that helps with the rash?

What is nausea situation? Nausea was the main side effect she experienced during prior chemo treatments, so she worries about nausea.

Does it effect your appetite? She barely eat anything now. I worry how the new pills will effect the appetite.

Thanks again

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dodooya | @dodooya | Feb 11 10:02pm

Thank you for your sharing! I would like to ask whether 6236 should be taken all the time or will it rest for a period of time after 21 days?

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wulijingjing | @wulijingjing | 2 days ago

@mimimmx Is RMC-6236 a gastric-soluble or enteric-soluble formulation?

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