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Stem cells for chronic lumbar pain

Spine Health | Last Active: 4 hours ago | Replies (22)

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@annie1

Related but not totally the same, is there anything that can help with repairing nerve damage that is causing me alot of twitching and throbbing in my legs ? I have nerve damage at s5-L1.

Thanks
Anne

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Replies to "Related but not totally the same, is there anything that can help with repairing nerve damage..."

@annie1 It's complicated from what I'm reading. I found this literature about regrowth of damaged nerves. I don't know if a neurologist could help.

J Pharm Bioallied Sci
. 2021 Nov 10;13(Suppl 2):S913–S916. doi: 10.4103/jpbs.jpbs_182_21
Neuroscience of Peripheral Nerve Regeneration
https://pmc.ncbi.nlm.nih.gov/articles/PMC8686930/
This is their conclusion.

"The regenerated PNS neurons after injury return only to suboptimal function especially the nerve trunk which is close to spinal cord and far from target organ have guarded prognosis. In nerve injury, injured neurons regenerate at rate of 1 mm/1 day, at this rate reestablishment of sensory organ innervations or functional motor unit might take many months or even years. The late reestablishment of regeneration is called chronic axotomy, which may lead to chronic muscle denervation leading to irreversible atrophy of muscles and sensory organ, causing fat tissue replacement. Another failure of functional recovery of nerve is due to regeneration of axon into different end organ and endoneurial tubes. Physical exercise has shown to improve motor recovery of transected nerve, during its repair process. Besides exercise, ascorbic acid, and neurotrophic factors have shown positive neuritic outgrowth. Mesenchymal stem cells have shown good regenerative potential, in nerve regeneration, which will be an excellent tool for the same. Combinations of new strategies such as using regenerative medicine technologies can accentuate nerve regeneration process."