I took it for over 5 years. I had none of the digestive side effects (acid reflux) or joint pain. However, I fractured at T8 at just over five years. I have since learned that it suppresses bone formation along with bone resorption.

Our bones are constantly developing microfractures as we use them. The bone remodeling process is critical for repairing those microfractures. When this process is stopped, our bones slowly become more brittle and compromised. This is why a drug “holiday” is recommended after being on Fosamax.

I had excellent gains in my T-score the first two years I was on it but then they started to deteriorate. I feel that stopping all bone remodeling is risky, especially for people who are constantly stressing their bones with exercise and activity. I believe this drug contributed to my fracture after five years.

I am trying to continue anabolic treatment (4 months of Tymlos) and working through issues with insurance coverage.

I realize that bisphosphonate treatment is recommended after anabolics and I would consider taking Fosamax again for a brief period - maybe one year.

At any rate I have enough Alendronate in my bones to last for years after taking it for five years so I would perhaps not take it.

I've been taking Fosamax off and on for years. No side effects. You must be compliant and take it once a week or your won't see good results. Follow the directions carefully. I always wait an hour before I eat or drink. I don't take any calcium for at least 2 hours. Good luck!