Interesting, Ivgal, in that I am an 85-year-old Wisconsin male where alcohol is so ingrained in our culture that we are blinded to its ill effects. It's toxic to the human body, yet warnings are muted because the industry lobby is so strong (parallel to the NRA keeping gun control muted). I had an alcoholic father so I was quite aware of how bad extreme use was so "having a few beers at the end of the work day" seemed pretty normal and harmless. Excluding some pretty heavy beer drinking in college, having a beer or two (maybe 3 or 4 when company called) was my guide. No tavern sitting, no weekend binges, and certainly no booze hidden around the house! Imagine my surprise at age 75 when a new doctor, upon hearing of my drinking history of drinking 6-8 beers a week, wrote down "alcohol dependent!" (The doctor was not from Wisconsin!) I was diagnosed with peripheral neuropathy caused by long-term use of alcohol. Later neurological tests confirmed the diagnosis. While I quit alcohol use immediately, the numbness has progressed (no pain and no impact on balance) to mid-calf with the intensity lessened with daily doses of super vitamin B-complex and 300 mg R-Lipolic Acid (with Biotin optimizer). With my doctor's approval, I have just started a monthly trial of 10,000 mcg (10 mg) of Biotin.