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Adverse effects of ADT for aggressive tumors

Prostate Cancer | Last Active: 4 days ago | Replies (18)
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@shelby29

I was taken off zytiga after 11 months because I suffered a heart attack. (Gleason 8 with cribiforms, stage 3tb)
Do lutamides affect the heart like zytiga?

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Replies to "I was taken off zytiga after 11 months because I suffered a heart attack. (Gleason 8..."
northoftheborder | @northoftheborder | 4 days ago

Prolonged QT interval is a rare but observed side-effect for Apalutamide, at least. I don't know how it compares to Zytiga, heart-wise, but at least you don't have to take a steroid with it, which might be helpful.

It would be a good question to ask both your oncologist and your cardiologist

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northoftheborder | @northoftheborder | 4 days ago

I should add some personal experience. For two months in 2022–23, it was mistakenly thought that I'd had a heart attack at some point in the recent past (presumably in the wake of my emergency surgery and post-surgical complications in 2021), until further tests and a review of the original TTE imagery reversed the verdict.

During those two months, they did not take me off Apalutamide, or even float the idea that staying on it might be an issue.

Your mileage may vary.

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