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Cavitary MAC - what makes cavity shrink?

MAC & Bronchiectasis | Last Active: 1 day ago | Replies (30)
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@helen1000

wolfplanetzero,
Amikacin Inhaled is much cheaper than Arikayce, per my research, and probably you can afford it. Yes please keep me posted of your doctor's answer about thick walled cavity. I have heard stories about thick walled collapsed or not collapsed, different stories.
Are you sensitive to Amikacin? What is your drug test result? I am sensitive to arikayce inhaled but not sensitive to amikacin IV. If you can let me know your value, that will be helpful.

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Replies to "wolfplanetzero, Amikacin Inhaled is much cheaper than Arikayce, per my research, and probably you can afford..."
wolfplanetzero | @wolfplanetzero | 3 days ago

The mac sample was shown to be vulnerable to amikacin and Arikayce. Because I was recently diagnosed with Parkinson's, my ID doc wants me to use an inhaled version of the medication instead of IV since there is less of a chance of neurological side effects.
Regarding the new research article posted by Carolyn, there is a recent mouse study that showed that the diabetes drug Metformin could be beneficial against MAC. What works on mice doesn't always help humans, but perhaps someone will fund a clinical trial.
https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2024.1463224/full

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