Hi packman7 - Not much to add to my comments to douglasmayo other than agreeing that a Decipher test would probably be a good idea and may sway your treatment decision. I have not yet checked into proton guided radiation and am probably not a good candidate for focal therapy with my cancer not being localized and in one place. Your 8 of 12 positive cores and 16 psa certainly confirms that you have cancer but before deciding on a definite treatment you might want to attempt to find out about the genomic makeup of that cancer with Decipher or one of the similar tests. Bottom line is that everyone is different and everyone needs to become comfortable with his own treatment decision. I’m probably leaning towards surgery given my very high risk decipher result and strong family history and notwithstanding low risk clinical markers but I just want the best chance of avoiding recurrence.
Best of luck in your journey.