← Return to Anyone taking Capecitabine Chemo for bile duct cancer?

Discussion

Anyone taking Capecitabine Chemo for bile duct cancer?

Liver Cancer | Last Active: 14 hours ago | Replies (22)
Comment receiving replies
@denise134

Had left lobe liver removed Sept 6, no symptoms before found on pelvic scan. Surgery went well but month later I started capecitabine 1,950 mg twice daily for 13 days and I quit - had severe mucositis bleeding gums and nose plus sick in stomach no appetite then diarrhea and blisters scabs on chest so- so they reduced dosage 1500 twice a day seemed a little better then got sinus infection went on strong antibiotic so off pills 18 days them did third dose - mucositis milder then hands swollen feet peeling and diarrhea from hell - lost all control and couldn't walk for 3 days and Imodium didn't help much so now oncologist testing me for DPD gene and waiting to see if I can't tolerate anymore - maybe new treatment?? Supposed to be well tolerated pill so anyone else have severe issues early on with capecitabine??

Jump to this post

Replies to "Had left lobe liver removed Sept 6, no symptoms before found on pelvic scan. Surgery went..."
sunflower88 | @sunflower88 | 3 days ago

Hi Denise,
My husband had his left lobe of his liver removed on 6/24/24, started taking capecitabine 2000 mg twice a day in August, 2024. His feet peeled and some of his fingers as well. Then he got severe diarrhea like 7-10 times a day. Lost 18 lbs in less than 3 weeks. Had to go to Mayo ER for IV hydration with potassium. He was taking Imodium, and pepto bismol, no relief. His team of doctors and PA had him stop oral chemo for a month. They finally prescribed Loperamide for the diarrhea. Slowly it helped. When he started back on the oral chemo they reduced it to 1500 mg twice a day. He is able to tolerate the lower dosage much better. He still has diarrhea occasionally but nothing like before. He was on the BRAT diet when it was bad, he also had 2 more IV hydrations with potassium (3 total). He will be on oral chemo capecitabine for a total of 6 months. With 2 weeks on chemo, followed by 1 week off of chemo for 6 months. He has 2 months left. Bile duct cancer has a high recurrence rate. Blood work every 3 weeks, every 2 months he has an MRI and a CT Scan on his chest. Tumor markers are done with blood work, so far so good. Cancer has not come back yet and it was caught very early.Stage 1 \ Grade 1B. The malignant tumor on his liver was big at 6 cm.

I hope this info helps.

VIEW AND REPLY