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Small Fiber Neuropathy and Epstein-Barr Virus

Neuropathy | Last Active: 2 days ago | Replies (35)

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@inmagic

I am convinced that the herpes viruses of Epstein-Barr and Varicella-Zoster do cause small fiber neuropathy. I have no positive autoimmune results in any blood tests or spinal fluid, but I was born with a natural killer cell (NK cell) deficiency. NK cells fight all the herpes viruses and cancer tumors. I grew up with non-stop mono and strep infections and developed chronic recurring Varicella-Zoster when I was 26. I came down with sudden onset SFN symptoms in 2011 (when I was 50) and acute polyneuropathy (GBS) in 2015. I live with a pages-long list of small fiber and autonomic neuropathy symptoms that no neurologist has yet to confirm as SFN because my preliminary tests for autoimmune are negative, and my first punch biopsy was also negative. My symptoms are worsening and debilitating. I am seeing yet another new neurologist this month, one that will hopefully listen. So far, when I mention NK cell deficiency, EBV, or Varicella Zoster, even at the Mayo Clinic (2016), they look at me like I am crazy and say there is no evidence. I am compiling evidence. If you would like to share notes about what we have found, I am happy to do so.

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Replies to "I am convinced that the herpes viruses of Epstein-Barr and Varicella-Zoster do cause small fiber neuropathy...."

I think I am in a similar boat. After years of viral infections when I was younger, and then a confirmed lengthy bout with epstein-barr about 5 years ago, followed by a period with covid and long covid, I have peripheral neuropathy. All of my doctors except for my PCP look at me like I am being ridiculous when I bring these viruses up. My PCP takes it seriously, but there is not much he can do about it. The only things that seem to be helping me are a healthy, low sugar, low inflammatory diet and exercise every day.