Hello I have severe Adhesive Arachnoiditis & have severe constipation issues. My Dr prescribed Cymbalta 30mg. I couldn't go to the bathroom & doubled over with gas pains. Retired RN, so i know opioids cause constipation. It also gave me a weird, metallic taste & an even drier mouth than usual. I am also sensitive to a lot of medications. My pain is so bad, i can't get out of bed. keep going to ER for Dilaudid My pain management NP, not much help. Doctor prescribed 30 mg, but said he wanted me to go to therapeutic dose, which is 60 mg Not taking Cymbalta, as i just can't tolerate any more symptoms. He probably won't be too happy with me