Yes Rick. It is chronic and progresses sometimes. That brings us fear, anger and uncertainty in life. It is also hard to stay positive among these emotions. But new medicine and technology are also on the way. There is always a hope. I also encourage myself that it is a battle, a very hard battle and it needs a lot of courage, hope, self-encouragement and team work. If we can't cure it, we slow down its progress, which is also a success. We gain time for us, and that gives an opportunity too.