Hi @fibrogirl61

I've was on Cymbalta duloxetine 60 x 2 for approx five years (was experiencing severe back pain while walking and playing golf). This was several years ago. I began feeling much better in time (my back pain had reduced almost completely) so I decided that 60mg twice a day was likely more than I needed (it was just a guess), so one day I just dropped to 60mg x 1 (once a day), and didn't really notice any difference taking that dose. I have stayed on that dose until now. During the past few weeks I've had to switch from the Eli Lily Cymbalta to a generic (Lily stopped making Cymbalta suddenly), and it has been difficult. I'm slowly getting acclimated to the generic, and hope to have that resolved within the next month or so. Duloxetine has been a godsend medication for me over the past ten years. As for other medications, yes, I take others for rheumatoid arthritis but these meds do not conflict with duloxetine. All the best.